House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool
Home in Panamá
5.0 out of 5 average rating, 9 reviewsMajestic Villa in Las Montañas
Jan 30 – Feb 6
Home in Vacamonte
4.55 out of 5 average rating, 20 reviewsThe Soul House by AcoModo
Jun 5 – 12
Home in Panamá
5.0 out of 5 average rating, 5 reviewsBeautiful house in Brisas del Golf
Aug 17 – 24
Home in Vacamonte
4.57 out of 5 average rating, 7 reviewsAdorable and cozy 3 bedroom house in Playa Dorada
Jun 27 – Jul 4
Home in Vacamonte
4.89 out of 5 average rating, 19 reviewsCozy beach house close to town!
Sep 17 – 24
Home in Panama City
5.0 out of 5 average rating, 3 reviewsBeautiful 4 bedroom House with Pool!
Dec 25 – Jan 1
Home in Panamá
4.71 out of 5 average rating, 21 reviewsYour cottage, Mountain Menus, awaits.
Aug 22 – 29
Home in Vacamonte
4.67 out of 5 average rating, 3 reviewsNice Casa Entera for rent
Sep 30 – Oct 7
Weekly house rentals
Home in Panamá
4.86 out of 5 average rating, 14 reviewsAmazing mountain house
Feb 14 – 21
Home in Panamá
4.8 out of 5 average rating, 15 reviewsApartment in Obarrio
Dec 1 – 8
Home in Panamá
4.87 out of 5 average rating, 55 reviewsCozy 3BR Home in Ancon Hill's Lush Oasis
Dec 22 – 29
Home in Panamá
4.75 out of 5 average rating, 4 reviewsSpacious & cozy 4 bedroom home.
May 13 – 20
Home in Panamá
New place to stayHouse near the airport
Sep 3 – 10
Home in Panamá
5.0 out of 5 average rating, 3 reviewsCozy House in Panama - 10 minutes from the Airport
Sep 1 – 8
Home in Panamá
4.71 out of 5 average rating, 7 reviewsentire home!
Oct 19 – 26
Home in Panamá
4.83 out of 5 average rating, 40 reviewsRed House Altos de Cerro Azul
Jun 3 – 10
Private house rentals
Home in Panama City
4.92 out of 5 average rating, 13 reviewsLovelyviewPty House 15 minutes away from the airport.
Oct 24 – 31
Home in Panamá
4.5 out of 5 average rating, 16 reviewsCozy 1 bdr Apartment with A/C near Santa Maria
Mar 23 – 30
Home in Panama City
4.82 out of 5 average rating, 77 reviewsCASA DE LINA HOSPITALITY,TRANQUILITY AND COMFORT
Dec 20 – 27
Home in Veracruz
4.75 out of 5 average rating, 4 reviewsSpectacular luxury home near city, beach, mountain
Feb 22 – Mar 1
Home in Panamá
4.4 out of 5 average rating, 5 reviewshouse close to airport and shopping center
Oct 8 – 15
Home in Panamá
4.5 out of 5 average rating, 4 reviewsCottage in Panama
Jul 4 – 11
Home in Panamá
5.0 out of 5 average rating, 4 reviewsPleasant equipped house for Descanso or homeoffice
Aug 7 – 14
Home in Panamá
4.6 out of 5 average rating, 20 reviewsCan Colibrí - Villa in Cerro Azul - Jacuzzi&Sauna
Mar 2 – 9
Quick stats about house rentals in Panama City
Total rentals
420 properties
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
130 properties allow pets
Family-friendly rentals
160 properties are a good fit for families
Total number of reviews
4.5K reviews
Nightly prices starting at
$10 before taxes and fees
Destinations to explore
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- Family travel hub Tips and inspiration
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