Hotel vacation rentals in Los Santos Province

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Top-rated hotel rentals in Los Santos Province

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Private room in Cañas

5 out of 5 average rating, 8 reviews

Standard Suite

Representing each of the seven chakras and set in a circle, our suites are the ideal environment for alignment, balance and creativity. Each with a different spectacular view: the rolling hills of Cañas, sunrise, ocean, Isla Cañas and sunset, these domes offer A/C, an indoor loft, ensuite bathroom with hot water, and a private deck with star gazing net and/or outdoor living room. Suites can be arranged with 2 king beds, 1 king & 2 twin beds or 4 twin beds. No children under 16 allowed or pets

Hotel room in Santo Domingo

4.9 out of 5 average rating, 20 reviews

Nice Family Room in a Family Hostel

Comfortable double room, with two single beds, fully furnished, surrounded by a garden and comfortable hammocks and chairs. Located in a family hostel in Santo Domingo, Las Tablas. Family house is close to Las Tablas downton, beaches and landmarks. Ideal for visitors who appreciate quietness, nature, outdoors Some features: a/c, WiFi; bar Fridge; cable TV; cleaning service; hot water; spacious wardrobes. We're LGBT, solo, women, single & family and pet friendly. Welcome to our house!!

Superhost

Hotel room in La Enea

4.74 out of 5 average rating, 31 reviews

Private, open concept room with pool/beach access!

Looking for a private, open concept room with pool and beach access? The room has a queen size bed, bunk bed, and sofa bed with private bathroom. The 2nd floor balconies have pool/ocean views. The room is located at Playa Guarare, but is only a 20 minute drive to Las Tablas and 35 minutes to Chitre. On-site restaurant can provide daily meals. 2 minute walk to the beach and 3 minute walk to the port where you can hire a boat for fishing/whale watching. Hammocks and picnic tables available too!

Guest favorite

Hotel room in PA

4.88 out of 5 average rating, 25 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Superhost

Hotel room in Playa Venao

4.7 out of 5 average rating, 20 reviews

Estrella Room - Quiet, budget friendly - queen bed

Estrella Room is the perfect 2 person room for economical travelers looking to stay in paradise on a budget. With one queen bed, it is perfect for friends and family or solo travelers. This room is on the second floor, a quiet and peaceful space. Equipped with A/C and hot/cold water, you can come back to your room and sink into relaxation after a fun day in the Panama sun. *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host.*

Private room in Las Tablas

4.75 out of 5 average rating, 8 reviews

Hotel Villas Don Pablo / Las Tablas Villa N°2

Hostal Villas Don Pablo is an accommodation where you will be in contact with nature, where you can relax alone or with your family and pets. Just 11 minutes from our hostel we have a nice, clean and safe beach. The treehouse village is only 2 minute drive to our hostel. Our cabins have everything you need for a pleasant visit. We have WiFi throughout the hostel.

Guest favorite

Hotel room in Cambutal

5 out of 5 average rating, 5 reviews

Boutique Inn_The Hill 1_Private Entry_Sea View_16+

The Hill Panama, our Boutique Inn Adult Only (16+) is located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 1 was designed as a boutique hotel room with separated private entry and communal kitchen.

Guest favorite

Hotel room in Las Tablas Abajo

4.82 out of 5 average rating, 67 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.