Villa vacation rentals in Los Santos Province

Find and book unique villas on Airbnb

Top-rated villa rentals in Los Santos Province

Guests agree: these villas are highly rated for location, cleanliness, and more.

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Guest favorite

Villa in Las Escobas del Venado

5 out of 5 average rating, 8 reviews

Villa Tortugas Playa Venao

Enjoy a spectacular Villa, just a short 3-minute walk to the beach in the most exclusive gated community, with security guards, surveillance & parking. There are 2 bedrooms, each with a private bathroom and an extra bathroom for guests, full kitchen, living room, and a beautiful terrace to rest with friends and family. The house has a 65" Samsung Smart TV / Appe TV, 25MB Wi-Fi internet in each room, and air conditioning. Our facilities at the oceanfront clubhouse & restaurant are exquisite.

Superhost

Villa in Playa Venao

4.8 out of 5 average rating, 44 reviews

Villa Nomada -Barefoot Luxury Beach Front Villa

Ocean front, barefoot luxury, 5 rooms with king bed, 1 nanny's room with queen bed, equipped kitchen, 5 bathrooms and a private pool on the beach 🏝 Villa Nomada is a hand crafted masterpiece, for the new age Nomadic lifestyle. It’s unique architecture invites the outdoor in, Using local elements, built on site such as roof tiles & pottery, furniture, doors and decks. Follow us On IG @villanomada *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

Guest favorite

Villa in Playa Venao

4.94 out of 5 average rating, 34 reviews

Villa Verde - Luxury&Cozy Villa 1BR #26 BlueVenao

Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Guest favorite

Villa in Pedasí

4.78 out of 5 average rating, 23 reviews

Drones Pedasi Ranch - Beach Pool Folk Fest Fishing

FAMILY or couples will Relax at this peaceful on the beach complete Ranch. Restaurant near by or drive (5) min to Pedasi's Town Center or Children can be kept close, a bunk-bed is near the King Size bed, with TV and Disney channel in the spacious Main room . Two other bedrooms with two Double-Bed each. All rooms with Bathroom and closet. Separate Kitchen & Dinning room with a relaxing view of the Ocean and wilderness. Ask us about tours to Isla Iguana, fishing trip or Horse back-riding.

Superhost

Villa in Las Escobas del Venado

4.8 out of 5 average rating, 5 reviews

Villa Sirena - Blue Venao

Villa Sirena is a modern beach apartment in the most luxarious resort in Playa Venao - 'Blue'. Only 2 minute walking distance from the beach and an exclusive beach club where you will have access to a stunning beachfront infinity pool, delicious restarunt, and a spacious relaxation area. The Blue community is a relaxed, central and secure gated community where you will always be just a few minutes walking distance from the best restaurant, surfing spots, parties and of course - the beach!

Guest favorite

Villa in Playa Venao

4.98 out of 5 average rating, 63 reviews

Casa Aqua: Amazing beach front house - Playa Venao

Exceptional beach front property, Casa Aqua sits right on the beach of Playa Venao Bay where you can enjoy great surfing, fishing, whale watching and many other outdoor activities. Casa Aqua is a very spacious 3,500ft home with all amenities you could dream of. You will love to eat/lounge outside in the spacious covered terrasse or swim in the large infinity pool. And if you don't feel like cooking, there are some quality restaurants close by a short walk on the beach from Casa Aqua.

Guest favorite

Villa in Playa Venao

4.91 out of 5 average rating, 32 reviews

Villa La Piragua : 3BR Surfside Retreat : 5-7G

Welcome to Villa La Piragua, an enchanting sanctuary in Blue Playa Venao. Let yourself go in this tropical paradise with pristine beaches. This beautiful villa offers 3 comfortable bedrooms and 3 well appointed baths. Two bedrooms have dreamy queen beds, while the third features a bunk bed with a pullout and an additional twin bed. All bedrooms have smart TV's and WiFi. Enjoy a serene spacious atmosphere in the living area, kitchen, and terrace, ensuring a memorable family getaway.

Superhost

Villa in Playa Venao

4.89 out of 5 average rating, 19 reviews

Villa Best Located in Blue | With Private Pool

Vivienda en Playa Venao; con todo lo necesario para pasar unas excelentes vacaciones con familiares o amigos. 7 personas incluyendo bebés y niños. Se pueden adicionar personas con costo extra. La vivienda es parte de un proyecto privado con garita de seguridad y estacionamiento gratuito. Disfruta de Playa Venao, con sus magníficas olas, disfrutar de un tour a Isla Iguana, hacer yoga, comer delicioso, disfrutar de la vida nocturna y de la naturaleza... todo en este paraíso tropical.

Superhost

Villa in Las Escobas del Venado

New place to stay

Beachfront Villa with Pool at the Heart of Venao

Welcome to Villa Siete Grados, a stunning beachfront villa located just a short walk from the vibrant restaurants and activities of Playa Venao. Perfect for groups and families, this spacious five-bedroom retreat accommodates up to 14 guests in total comfort. While close to the action, the villa offers complete privacy, nestled in a serene, quieter area of the beach. Whether you're here to relax by the sea or explore the lively town, Villa Siete Grados offers the best of both worlds.

Villa in Pedasi

4.67 out of 5 average rating, 85 reviews

Super Private Beachfront 3BR Villa & Infinity Pool

Sky above, sand below, peace within ~ Welcome to la Dolce Vita! Located in Andromeda, an oceanfront gated community on the Azuero Peninsula. Andromeda villas offer amazing and unparalleled ocean views where you can be with the sights and sounds of nature at its most beautiful. Our sun-filled and stunning Villa is 3 bed / 3 bath for up to 8 guests. Features a spectacular view, private pool and direct beach access. Fully equipped so you can feel at home and enjoy your getaway!

Villa in Cambutal

4.56 out of 5 average rating, 25 reviews

Pacific Escape

Pacific Escape looks out over an expanse of pacific ocean and protected reef. The 2 bedroom, 2 full-bath home has panoramic views of the ocean, mountains, and reef. Yet, it is close to the beach, restaurants and dining, and family-friendly activities. You’ll love the expansive oceanside porch, high ceilings, the ocean views from bedrooms and living room, and the ambiance. The villa is great for couples and families (with kids) because it sits at the top of a private gated road.

Villa in Punta Mala

5 out of 5 average rating, 4 reviews

3-BR Villa with Infinity Pool

Experience luxury at our 3-bedroom waterfront retreat, just steps from the beach. This gated community home features panoramic Pacific Ocean views, a Salt Water Infinity pool, and spacious interiors fully furnished with high-end amenities. Each bedroom includes ensuite bathrooms, with the master suite offering a king-sized bed and walk-in closet. Enjoy a gourmet kitchen, outdoor gazebo with BBQ, Sonos speakers, and high-speed Wi-Fi throughout. Perfect for families and groups.