Vacation rentals with lake access in Alachua County

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Alachua County

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Melrose

5 out of 5 average rating, 9 reviews

Lakeside Suite

The Lakeside Suite consists of the ENTIRE 1800 SQUARE FOOT BOTTOM FLOOR of our spacious home on Lake Santa Fe. You'll have your own private entrance, facing the lake, a private porch and use of the dock and the beach. We also provide kayaks & canoes and lake access for swimming, sunning and relaxing. Our home is family friendly & it's also a great space for a private getaway or relaxing weekend. Me and my husband live upstairs and we have our own entrance and we're available if you need us.

Guest favorite

Guest suite in Melrose

5 out of 5 average rating, 11 reviews

Old FloridaVibes! Boat Parking/near Lake Santa Fe~

Kick back & relax in this calm, stylish space. Flexible stays, no cleaning fees, no check-out chores- Be Our Guest! Private guest suite, no shared walls for ultimate privacy. 2 acre lush, tropical property near Lake Santa Fe with plenty of room for boats. Dine al fresco in a screened oversized gazebo with BBQ grill & big dining table. Public boat launch 2 miles away- be underway & enjoying Lake Santa Fe in minutes. Small gatherings ok, with a heads up. Alachua County Tourist Tax license 1071.

Guest favorite

Home in Melrose

5 out of 5 average rating, 9 reviews

Modern LAKE HOUSE on Lake Santa Fe near Gville/UF

Have fun OR relax at this fully renovated LAKE HOUSE w/BOATHOUSE and raised sunset deck only 30 mins to Gainesville! Sit back and and enjoy the beautiful views of the lake as soon as you enter the home or up close from the hammock swings in the boat house! 3 BR/2 BA plus converted air conditioned garage used as a game room with Ping Pong Table and TV, easily sleeping 8. The backyard offers a large deck with privacy fencing and lush landscaping with direct access to step right into the lake.

Guest favorite

Cottage in Archer

4.94 out of 5 average rating, 36 reviews

The Glass House on Grassy Lake

The Glass House was built by local artist, Ira Winarsky. A charming waterfront lake house nestled on 12.5 acres with private access to the serene Grassy Lake is just 7 miles from Gainesville. This cozy retreat offers a perfect blend of nature and comfort, featuring a full kitchen, living room, and spacious deck with scenic views for an evening under the stars. Ideal for couples, adventurers, birdwatchers and Gator friends and fans alike. Seeking a peaceful escape? Come unwind and recharge.

Guest favorite

Cabin in Hawthorne

5 out of 5 average rating, 54 reviews

Creek House, connecting Orange&Lockaloosa Lakes

Enjoy Old Florida at its finest! The Creek connects 2 lakes; Orange & Lochloosa, known for outstanding Bass (Bassmasters 1 of the top 10 in US & #1 in SE for Bass) plus Crappie fishing! Use of private dock to keep boat tied. One mile from Marjorie Rawlings historic park is the boat ramp. Local attractions; Historic Micanopy, Island Grove winery, Ocala World Equestrian center 20 miles & 15 miles to UF/Gainesville. Hiking, biking & horse trails nearby. Springs in close driving distance.

Superhost

Home in Alachua

4.83 out of 5 average rating, 213 reviews

Gated Golf Getaway close to Springs and UF

A clean and comfortable home, situated in a gated community with a public golf course, reasonably priced restaurant, swimming pool (seasonally, quick walk or drive), playground, and tennis courts available to guests. The home features a gas fireplace and screened patio with table, chairs and grill. There are 3 bedrooms each with a queen bed. Located on U.S. highway 441 just 20 minutes from U.F. sports stadiums and Hospitals. Convenient shopping and restaurants 10 minutes by car.

Guest favorite

Cottage in Melrose

4.99 out of 5 average rating, 69 reviews

The Nest on Lake Santa Fe in Melrose, FL

The Nest is a beautiful two-story cottage on Lake Santa Fe. Enjoy some peace and serenity, catch monster bass, or bring your ski boat for high-speed fun. We are located just 20 minutes from Gainesville and UF. The Nest is great for a weekend getaway or a week of peaceful relaxation. We do not allow parties or events out of respect for our neighbors and we allow a maximum of 6 guests (max 4 adults). Absolutely no animals are allowed on the property at any time for any reason.

Guest favorite

Rental unit in Melrose

4.98 out of 5 average rating, 102 reviews

Lake View Apartment on Melrose Bay

Lake View Apartment This apartment is newly remodeled. It features new cabinets, a private porch and lovely furnishings, WI-FI and Cable. Downtown Melrose is within walking distance with three restaurants (one is the famous Blue Water Bay), public library, post office, grocery store and two dollar stores. Bring your boat and launch at the nearby boat ramp. Lake Santa Fe is a recreational lake with clean spring fed water for swimming, fishing, boating and skiing.

Guest favorite

Rental unit in Waldo

4.99 out of 5 average rating, 154 reviews

Fernbank on beautiful Lake Alto. Laketime Getaway

Visit this beautiful, tranquil lakeside spot for an amazing getaway. It's a six acre property, an inspiring place to study, write, or get work done with fun things to do while on a break. Swim, kayak, canoe, paddle board or enjoy sitting on the dock. Visit the barn for basketball, ping pong, and corn hole. It's a studio apartment with a private bathroom and beds for four, plus two couches and air beds available. Note: This is an upstairs apartment.

Guest favorite

Guest suite in Gainesville

4.97 out of 5 average rating, 70 reviews

Studio Guest House | 2BD 1BA | 4 min from UF

The Studio is a private guest house featuring luxury amenities. This open-concept retreat is centrally located with a private courtyard. Inside, enjoy a blend of modern and mid-century design, with glass sliders that create an inviting indoor-outdoor feel. Amenities include an LED vanity mirror, stainless steel towel warmer, Bluetooth speaker, glass dining table, convertible sleeper sofa, suspended pod chair, and Google Home display for added convenience.

Guest favorite

Rental unit in Melrose

4.99 out of 5 average rating, 81 reviews

Lakefront Retreat Apartment Remodeled, Premium Bed

Private lake home on Big Lake Santa Fe is the perfect place to unwind and enjoy gorgeous sunset views. The rental unit is an upstairs separated apartment. It has a cedar interior with a cabin feel has recently been renovated with new appliances, flooring and updated bathroom with walk in shower. Bring your boat to cruise the lake or fish and tie up at our dock. Enjoy swimming, water skiing, fishing or just relaxing on the deck.

Guest favorite

Camper/RV in Hawthorne

4.97 out of 5 average rating, 86 reviews

Private Lake Camper with dock/kayaks and patio

Beautiful lake front home on Little Orange Lake offering guided fishing and boat rentals. Camper located in private area of property overlooking the lake that has the most beautiful sunrises, Excellent fishing off the dock, and kayaks/paddle boards to cruise around this hidden gem in N central Florida. This lake offers excellent fishing. 2 Patios and Boat slip included. Rental for the pontoon is $250/day