House vacation rentals in DeSoto County
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Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool
Home in Venice
4.89 out of 5 average rating, 163 reviewsVenice Pool Villa with Bikes Kayaks Great Beaches!
Home in Punta Gorda
4.96 out of 5 average rating, 205 reviewsTropical getaway Pool and tiki bar
Home in Port Charlotte
4.85 out of 5 average rating, 214 reviewsPeaceful Port Charlotte 2Bd/2Ba on water
Home in Venice
4.89 out of 5 average rating, 185 reviewsPerfect vacation home 3 miles from beach.
Home in Venice
4.85 out of 5 average rating, 136 reviewsGetaway Relax Home/Beaches 5-10minutes/Heated Pool
Home in Port Charlotte
4.94 out of 5 average rating, 109 reviewsLuxury Bungalo with Pool in Port Charlotte
Home in Sebring
4.79 out of 5 average rating, 14 reviewsThe Little Retreat
Home in Port Charlotte
4.79 out of 5 average rating, 34 reviewsOasis with pool in the middle of West Coast, FL
Weekly house rentals
Home in Arcadia
5.0 out of 5 average rating, 5 reviewsHistoric Wheeler House
Home in Arcadia
5.0 out of 5 average rating, 26 reviews"Old Florida" Getaway
Home in Venus
4.95 out of 5 average rating, 37 reviewsThe Deer Retreat at Venus
Home in Arcadia
4.92 out of 5 average rating, 37 reviews2 Bedroom Country Home with Porch
Home in Punta Gorda
4.9 out of 5 average rating, 30 reviewsHouse in Punta Gorda: Hot tub, Patio, Pet Friendly
Home in Port Charlotte
4.96 out of 5 average rating, 24 reviewsSimply Summer
Home in Punta Gorda
5.0 out of 5 average rating, 15 reviewsCentral location close to I75, airport & downtown.
Home in Lake Placid
4.97 out of 5 average rating, 92 reviewsHome in quiet area with lake access
Private house rentals
Home in Punta Gorda
5.0 out of 5 average rating, 15 reviewsFlorida Paradise House
Home in North Port
4.96 out of 5 average rating, 47 reviewsBeautiful new build in North Port
Home in Punta Gorda
5.0 out of 5 average rating, 23 reviewsPunta Paradise: Comfortable Home Near Downtown
Home in Port Charlotte
4.9 out of 5 average rating, 82 reviewsCoastal Getaway – 3bed/2bath House with Pool
Home in Englewood
5.0 out of 5 average rating, 25 reviewsClean & Comfy Beach Cottage super-close to Gulf!
Home in North Port
5.0 out of 5 average rating, 18 reviewsEntire light filled Florida 2 bedroom/2 bath home
Home in Port Charlotte
4.95 out of 5 average rating, 19 reviews♥Pet Friendly ✔ Close to shops ☀10 mins to beach☀
Home in Punta Gorda
4.86 out of 5 average rating, 14 reviewsUnique 3 Beds Waterfront/dock/fish/family friendly
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