Guesthouse vacation rentals in Doña Ana County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Doña Ana County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 253 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill. Onsite owners as casita is adjacent to our main home.

Guest favorite

Guesthouse in Las Cruces

4.95 out of 5 average rating, 103 reviews

Contemporary Casita

Located in Picacho Hills Country Club area, 5 miles from Mesilla, 8 miles to NMSU, on the “View of Gold” cul-de-sac. Enter through private gate, native desert that surrounds the house and casita where quail, rabbits, lizards even occasional deer appear. Contemporary 1 bedroom/1 bathroom cozy casita w/full kitchen. Covered patio w/BBQ & heated table. Queen size bed, comfortable chairs, sofa & recliner. Large TV in living room & bedroom. Hot tub access available. Make yourselves at home.

Guest favorite

Guesthouse in El Paso

4.98 out of 5 average rating, 207 reviews

Cozy Modern Casita-Studio!

Perfectly located in Central El Paso! Found near the Franklin Mountain range, Downtown El Paso, great restaurants, sporting arenas, multiple hospitals, Fort Bliss Army base, and much more! Conveniently near multiple freeways for quick access to surrounding locations! -Newly renovated -Equipped with new modern appliances -Washer and dryer -Refrigerated air and heating -Comfortable queen bed -Sleeper sofa to accommodate a 3rd guest or children -Pack n’ play available for extra fee by request

Guest favorite

Guesthouse in Las Cruces

4.95 out of 5 average rating, 126 reviews

Quaint casita for 2

Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport. Aug 2024 ~ New mini split A/C installed.

Guest favorite

Guesthouse in El Paso

4.91 out of 5 average rating, 129 reviews

Beautifully designed Tiny Home

Beautifully designed space, perfect for a weekend getaway, business trip, or extended stay. Our tiny home is furnished with everything you need to feel truly at home.It's located in Military Heights historic district and Centrally located to the airport, Fort Bliss military base, downtown and with a view of Franklin MTN. Nearby theres authentic Mexican bakeries , restaurants and shops. Downtown/ UTEP/airport approx. 10 min away.Let this beautiful Tiny home be your next Airbnb!

Guest favorite

Guesthouse in Las Cruces

5 out of 5 average rating, 236 reviews

Desert Peaks Casita

This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 295 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Guest favorite

Guesthouse in Las Cruces

4.93 out of 5 average rating, 196 reviews

Casita Azul, 1 king bed, dogs and kids welcome!

Welcome to Casita Azul, this wonderful cozy space has everything you will need for a short or long stay. Full kitchen, one bedroom with a king bed, shower bath, living/dining room, streaming TV and internet. Small outdoor space so your fur babies are welcome! The entire casita has been remodeled but feels like a wonderfully funky space complete with hand painted Mexican tile. One block from the incredible Farmer's market and the downtown with shopping and restaurants.

Guest favorite

Guesthouse in Las Cruces

4.97 out of 5 average rating, 283 reviews

Clara's Nest - The Gem of Hacienda de Las Cruces

Clara’s Nest is in a 1880's adobe compound with its own private entry, courtyard, original stone floors, handcrafted beams, hand-painted bird & flower motif throughout. The suite features a king bed, cozy loveseat & ottoman in the sleeping area, dining table & 4 chairs, kitchenette with micro, fridge, coffee & tea bar, a separate living room with sofa, TV, private bath. Outer space includes: covered patio, backyard, pool and hot tub area (heated upon request) No stove.

Guest favorite

Guesthouse in El Paso

4.91 out of 5 average rating, 181 reviews

Comfortable Casita - Located Near Downtown/UTEP!

Welcome to our charming casita in the heart of El Paso, Texas! Located in the safest neighborhood, our cozy home is the perfect retreat for couples or solo travelers looking for a peaceful getaway. Relax in our beautifully appointed living space, prepare meals in the kitchenette, or unwind in the comfortable bed. Enjoy the convenience of our prime location, with easy access to local attractions and restaurants. Book your stay today and experience the best of El Paso!

Guest favorite

Guesthouse in Hatch

4.96 out of 5 average rating, 138 reviews

Casita at Old Mission near Hatch NM

Have you stayed overnight in a Church before? This is your opportunity. Your lodging in the Casita is attached to the now deconsecrated St Francis de Sales Church, surrounded by a large Spanish courtyard, garden, and a private patio and parking area. Experience the adobe spaces as built in 1860. The church compound is walled and gated. We are located 1 mile east of Hatch in a colonia called Rodey. Look for the bell tower from Hwy 185 and begin your experience here.

Guest favorite

Guesthouse in Las Cruces

4.99 out of 5 average rating, 143 reviews

Yucca Casita in Historic Mesilla

We have created a vision for this property of sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.