James Island vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in James Island
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for James Island vacation rentals
Other great vacation rentals in James Island
Apartment in Charleston
4.88 out of 5 average rating, 504 reviewsMinutes to Historical Charleston and Folly Beach!
Guest suite in Charleston
4.97 out of 5 average rating, 237 reviewsBoho Bungalow
Guesthouse in Charleston
4.93 out of 5 average rating, 708 reviewsCharleston's Coolest Neighborhood
Guest suite in James Island
4.94 out of 5 average rating, 1016 reviewsNewly Renovated Guest Suite with Exterior Entrance
Guesthouse in Charleston
4.91 out of 5 average rating, 126 reviewsCenterville Loft, Studio Apt on James Island
Guesthouse in Johns Island
5.0 out of 5 average rating, 104 reviewsCozy Getaway Nestled in Nature
Tiny home in Charleston
4.97 out of 5 average rating, 152 reviewsThe Berry Patch on James Island
Guesthouse in Charleston
4.97 out of 5 average rating, 221 reviewsLady Ashley Studio Apartment minutes to downtown
Other great vacation rentals in James Island
Tiny home in James Island
4.96 out of 5 average rating, 765 reviewsThe Cedar House Rules
Guest suite in James Island
4.97 out of 5 average rating, 115 reviewsLowcountry Suite-Marsh view/near Downtown & Beach
Home in Charleston
4.99 out of 5 average rating, 123 reviewsPerfect 1-Bedroom Guest Suite - Great Amenities!
Guest suite in Charleston
4.9 out of 5 average rating, 415 reviewsPrivate Suite - Near Beach & Downtown
Guest suite in James Island
4.9 out of 5 average rating, 200 reviewsLowcountry Island Loft - King Bed!
Guesthouse in James Island
5.0 out of 5 average rating, 216 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Charleston
4.91 out of 5 average rating, 170 reviewsRiverland Terrace Guesthouse
Tiny home in James Island
4.93 out of 5 average rating, 104 reviewsLovely Tiny House in Iconic Riverland Terrace
Destinations to explore
- Savannah Vacation rentals
- Hilton Head Island Vacation rentals
- Kiawah Island Vacation rentals
- Tybee Island Vacation rentals
- Folly Beach Vacation rentals
- Surfside Beach Vacation rentals
- Mount Pleasant Vacation rentals
- Hilton Head Vacation rentals
- Beaufort Vacation rentals
- Atlanta Vacation rentals
- Charleston Vacation rentals
- Myrtle Beach Vacation rentals
- Villa rentals James Island
- Rentals with a fireplace James Island
- Kid-friendly rentals James Island
- Rentals with a patio James Island
- Rentals with breakfast James Island
- Guesthouse rentals James Island
- Family-friendly rentals James Island
- Rentals with a kayak James Island
- Rentals with a hot tub James Island
- Beachfront rentals James Island
- Monthly Rentals James Island
- Rentals with lake access James Island
- House rentals James Island
- Townhouse rentals James Island
- Private suite rentals James Island
- Waterfront rentals James Island
- Rentals with an EV charger James Island
- Rentals with outdoor seating James Island
- Condo rentals James Island
- Pet-friendly rentals James Island
- Rentals with a fire pit James Island
- Bed and breakfasts James Island
- Apartment rentals James Island
- Rentals with beach access James Island
- Rentals with a washer and dryer James Island
- Fitness-friendly rentals James Island
- Rentals with pools James Island
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes