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Boutique hotel vacation rentals in Missouri
Find and book unique boutique hotel rentals on Airbnb
Top-rated boutique hotel rentals in Missouri
Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Missouri boutique hotel rentals
Family-friendly boutique hotels rentals
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Hotel room in Hermann
4.81 out of 5 average rating, 43 reviewsHermann Crown's Victorian Suite, Tons of Amenities
![](https://a0.muscache.com/im/pictures/06653c30-9b86-4f61-af46-3db2d2b6a6ec.jpg?im_w=720)
Hotel room in La Plata
4.85 out of 5 average rating, 26 reviewsDepot Inn & Suites - King Room
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Hotel room in Saint Louis
4.87 out of 5 average rating, 594 reviewsEvergreen Room Queen Bed at BnB in CWE
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Hotel room in Saint Louis
4.85 out of 5 average rating, 724 reviewsThe Maple Room Queen Bed at BnB in CWE!
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Hotel room in St. Louis
4.87 out of 5 average rating, 651 reviewsBlue Spruce Room Queen Bed at BnB in CWE!
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Hotel room in Hermann
4.95 out of 5 average rating, 37 reviewsHermann Crown's New Pet Friendly Shepherd's Suite
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Hotel room in Hermann
4.79 out of 5 average rating, 29 reviewsHermann Crown's 2 Bedroom Executive Vineyard Suite
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Hotel room in Hermann
4.79 out of 5 average rating, 29 reviewsHermann Crown's Presidents Suite, 3 Beds & 2 Baths
Boutique hotels rentals with a patio
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Hotel room in Saint Charles
4.81 out of 5 average rating, 142 reviews1st Capitol Mansion Boutique Hotel - Suite 201
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Hotel room in Ste. Genevieve
4.9 out of 5 average rating, 21 reviewsThe Inn at Weingarten luxurious suites room #1
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Hotel room in Ste. Genevieve
Our Little Gemm at The Inn
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Hotel room in Osceola
5 out of 5 average rating, 4 reviews"The Quiet Room" #26 in a mid 1800s Hotel.
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Hotel room in Osceola
4.63 out of 5 average rating, 8 reviewsHistoric Commercial Hotel(Est.1868)"The Dam Room"
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Hotel room in Versailles
4.69 out of 5 average rating, 16 reviewsSecluded Rustic theme Hotel - Queen room
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Hotel room in Osceola
5 out of 5 average rating, 8 reviewsHistoric Commercial Hotel(1868)Karolyn Grimes Room
![](https://a0.muscache.com/im/pictures/202094e1-f769-4434-82bd-a7beba780075.jpg?im_w=720)
Hotel room in Versailles
4.5 out of 5 average rating, 6 reviewsA Secluded, Rustic Theme Hotel 4 Full size beds
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