Guesthouse vacation rentals in Charleston County
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Top-rated guesthouse rentals in Charleston County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 346 reviewsCozy Park Circle, Charleston Guest House
Aug 30 – Sep 6
Guesthouse in Summerville
4.98 out of 5 average rating, 643 reviews★Delightful guest house near historic plantations★
Mar 20 – 27
Guesthouse in Summerville
4.94 out of 5 average rating, 212 reviewsNina's Cottage -Historic Downtown Summerville
Dec 24 – 31
Guesthouse in Ridgeville
4.82 out of 5 average rating, 213 reviewsPond House Bungalow at Natural Gathering Grounds
Nov 2 – 9
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 220 reviewsGreen Garden Studio @greengardenstudio2017
Sep 18 – 25
Guesthouse in Charleston
4.91 out of 5 average rating, 648 reviewsIsland Oasis—Near Downtown
Oct 21 – 28
Guesthouse in Summerville
4.87 out of 5 average rating, 748 reviewsNew Loft in Historic Summerville
Mar 22 – 29
Guesthouse in North Charleston
5.0 out of 5 average rating, 111 reviewsThe Park Circle Clerestory Studio Guest House
Jun 21 – 28
Guest house rentals with a patio
Guesthouse in Charleston
4.97 out of 5 average rating, 127 reviewsStudio Apartment Minutes to Downtown Charleston
Feb 9 – 16
Guesthouse in Charleston
4.98 out of 5 average rating, 122 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Jan 21 – 28
Guesthouse in Johns Island
4.91 out of 5 average rating, 105 reviewsCozy Cottage! 5 mins from Kiawah!
Sep 18 – 25
Guesthouse in Charleston
4.98 out of 5 average rating, 45 reviewsCountry in the City, "The Outback"
Apr 21 – 28
Guesthouse in Goose Creek
4.96 out of 5 average rating, 49 reviewsThe Blue Secret
Jun 18 – 25
Guesthouse in Hanahan
4.99 out of 5 average rating, 76 reviewsThe Violet Villa w/ no cleaning fee
Aug 6 – 13
Guesthouse in Charleston
4.94 out of 5 average rating, 78 reviewsSpacious 1 bedroom cottage in Avondale
Dec 11 – 18
Guesthouse in Charleston
5.0 out of 5 average rating, 12 reviewsLowcountry Guesthouse
Jul 15 – 22
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.99 out of 5 average rating, 142 reviewsLarge Guesthouse with Private Dock & Marsh Views
Jun 10 – 17
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 436 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Nov 2 – 9
Guesthouse in Charleston
5.0 out of 5 average rating, 143 reviewsThe Guesthouse at Old Orchard
Sep 20 – 27
Guesthouse in North Charleston
4.94 out of 5 average rating, 111 reviewsNewly Renovated Studio in Park Circle
Jun 2 – 9
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 248 reviewsUpscale Couple's Escape | Beach & Downtown CHS
Jul 5 – 12
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 116 reviewsBeach, downtown, Alhambra Hall weddings so close!
Aug 25 – Sep 1
Guesthouse in Charleston
4.9 out of 5 average rating, 548 reviewsCute, Cozy, Charleston Cottage
Aug 3 – 10
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 258 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Jul 16 – 23
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