House vacation rentals in South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in South Carolina
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina house rentals
House rentals with a pool
Home in Aiken
4.85 out of 5 average rating, 102 reviewsCountry home with pool
Home in Folly Beach
4.95 out of 5 average rating, 153 reviewsLuxury Beach Living With Heated Pool
Home in Summerton
4.97 out of 5 average rating, 112 reviewsLuxurious Lakefront Log Home W/Pool & hot tub
Home in Charleston
4.98 out of 5 average rating, 113 reviewsWaterfront Privacy, heated infinity pool, location
Home in Johns Island
4.88 out of 5 average rating, 397 reviewsCharleston, SC-2 BR Guest Suite w/ Separate Entry
Home in Inman
4.95 out of 5 average rating, 102 reviewsMaggie's Lake House
Home in North Myrtle Beach
4.94 out of 5 average rating, 124 reviewsOceanview 4/2, XL pool/hot tub, steps to beach!
Home in Saint Helena Island
4.99 out of 5 average rating, 108 reviewsThe Hampton House
House rentals with free parking
Home in Surfside Beach
4.93 out of 5 average rating, 178 reviewsNanny & Pops cozy beach cottage -3 blocks to beach
Home in Newberry
4.97 out of 5 average rating, 153 reviewsNice CLEAN close to I26 downtown Newberry quiet
Home in Pendleton
4.99 out of 5 average rating, 108 reviewsPerfect 2 bed, remodeled home in quaint Pendleton
Home in Columbia
4.98 out of 5 average rating, 131 reviews✷ Dazzling Downtown Deco ✷ 2 BD 1 BA Home
Home in Georgetown
4.98 out of 5 average rating, 123 reviewsCarolina Wren Cottage: New, Relaxing, Dog-Friendly
Home in Folly Beach
4.97 out of 5 average rating, 173 reviewsThe Folly Haven
Home in Saluda County
4.9 out of 5 average rating, 106 reviewsLouie’s Paradise
Home in Spartanburg
4.92 out of 5 average rating, 277 reviewsbeautiful nature,3bedroom, 2 king and 2 queen beds
House rentals with a hot tub
Home in Santee
4.97 out of 5 average rating, 140 reviewsSantee lakefront home, big water right off I-95
Home in Inman
4.93 out of 5 average rating, 229 reviewsLakingitEz..3BR/2BA amazing sunsets & hot tub
Home in Inman
4.95 out of 5 average rating, 101 reviewsCasa del Lago...Come Relax...You are on Lake Time!
Home in Hilton Head Island
4.97 out of 5 average rating, 107 reviewsLovely 3BR in Palmetto Dunes w/ new pool & spa
Home in Pickens
4.83 out of 5 average rating, 130 reviewsPrivate Cabin Getaway with all the Amenities!
Home in Salem
5.0 out of 5 average rating, 101 reviewsKeowee Key Luxury Condo - Stunning Views!
Home in Modoc
4.93 out of 5 average rating, 104 reviewsIvy’s Escape (water front) at Lake Thurmond
Home in Mount Pleasant
4.93 out of 5 average rating, 108 reviewsPleasant Place: Newly Built with Pool: Close to downtown/beach
Destinations to explore
- Lighthouse rentals United States
- Guesthouse rentals United States
- Townhouse rentals United States
- Earth house rentals United States
- House rentals United States
- Rentals with lake access South Carolina
- Serviced apartment rentals South Carolina
- Rentals with beach access South Carolina
- Farmstay rentals South Carolina
- Lakehouse rentals South Carolina
- Aparthotel rentals South Carolina
- Resort rentals South Carolina
- Tiny house rentals South Carolina
- Campsite rentals South Carolina
- Loft rentals South Carolina
- Condo rentals South Carolina
- Waterfront rentals South Carolina
- Private suite rentals South Carolina
- Rentals with a sauna South Carolina
- Cottage rentals South Carolina
- Cabin rentals South Carolina
- Kid-friendly rentals South Carolina
- Rentals with a kayak South Carolina
- Townhouse rentals South Carolina
- Hotel rentals South Carolina
- Luxury rentals South Carolina
- Rentals with a fireplace South Carolina
- Rentals with pools South Carolina
- Rentals with a fire pit South Carolina
- Apartment rentals South Carolina
- Monthly Rentals South Carolina
- Rentals with breakfast South Carolina
- Bungalow rentals South Carolina
- Family-friendly rentals South Carolina
- Beach house rentals South Carolina
- Guesthouse rentals South Carolina
- Beach condo rentals South Carolina
- Rentals with a home theater South Carolina
- Bed and breakfasts South Carolina
- Pet-friendly rentals South Carolina
- Rentals with an accessible height toilet South Carolina
- Rentals with outdoor seating South Carolina
- Boutique hotel rentals South Carolina
- Hostel rentals South Carolina
- Rentals with a washer and dryer South Carolina
- Villa rentals South Carolina
- Fitness-friendly rentals South Carolina
- Rentals with a patio South Carolina
- RV rentals South Carolina
- Beachfront rentals South Carolina
- Rentals with an EV charger South Carolina
- Rentals with a hot tub South Carolina
- Smoking-friendly rentals South Carolina
- Wheelchair accessible rentals South Carolina
- Rentals with an accessible height bed South Carolina
- Townhouse rentals Charlotte
- Tiny house rentals Charlotte
- House rentals Charlotte
- Guesthouse rentals Charlotte
- House rentals Greenville
- Lakehouse rentals Greenville
- Guesthouse rentals Greenville
- House rentals Columbia
- Lakehouse rentals Columbia
- Guesthouse rentals Columbia
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes