House vacation rentals in DeSoto County
Find and book unique houses on Airbnb
Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool
Home in Memphis
5 out of 5 average rating, 23 reviewsMemphis Countrywood
Home in Shelby County
4.88 out of 5 average rating, 16 reviewsThe Memphian Manor - Your Private Estate
Home in Memphis
5 out of 5 average rating, 36 reviewsVacation Destination-sauna/hot tub/5 full baths!
Home in Memphis
4.91 out of 5 average rating, 55 reviewsEntire Estate in the Heart of Memphis!
Home in Memphis
4.93 out of 5 average rating, 41 reviewsSecret Garden of Memphis LLC
Home in Memphis
5 out of 5 average rating, 15 reviewsHoliday Home-15 mins to Downtown Memphis-Luxury
Home in Memphis
4.98 out of 5 average rating, 41 reviews2 br townhouse near South Main w/private garage
Home in Southaven
4.98 out of 5 average rating, 41 reviewsCori's Pool House
Weekly house rentals
Home in Southaven
5 out of 5 average rating, 7 reviewsSouthern Charm Comfort
Home in Southaven
4.69 out of 5 average rating, 16 reviewsSouthern Charm near Silo Square
Home in Southaven
5 out of 5 average rating, 4 reviewsCharming cozy townhouse
Home in Hernando
5 out of 5 average rating, 12 reviewsperfect place for travelers
Home in Southaven
4.91 out of 5 average rating, 22 reviewscenter of southaven home
Home in Horseshoe Lake
4.8 out of 5 average rating, 84 reviewsThe Hideaway at Horseshoe Lake
Home in Hernando
4.7 out of 5 average rating, 40 reviewsVictorian Hernando Home ~ 25 Miles to Memphis
Home in Olive Branch
4.77 out of 5 average rating, 62 reviewsSerenity Staycation
Private house rentals
Home in Lake Cormorant
4.5 out of 5 average rating, 4 reviewsFarmhouse Meadows
Home in Olive Branch
5 out of 5 average rating, 21 reviewsENTIRE HOME LESS THAN 1 MIN FROM MEMPHIS
Home in Memphis
4.91 out of 5 average rating, 11 reviewsCOZY meet LUX in the Suburbs and Ambience begins!
Home in Olive Branch
4.55 out of 5 average rating, 11 reviewsGreat Home in Quiet Olive Branch #869
Home in Southaven
5 out of 5 average rating, 4 reviewsLuxury Mansion with King beds, garden and pool
Home in Hernando
New place to stayPeace of Heaven on a Hill
Home in Southaven
4.61 out of 5 average rating, 254 reviewsSpacious 5 bedroom house, close to Snowden Grove
Home in Horn Lake
4.73 out of 5 average rating, 11 reviewsNice three bedroom spacious home.with fun room.
Destinations to explore
- Lighthouse rentals United States
- Guesthouse rentals United States
- Earth house rentals United States
- Townhouse rentals United States
- House rentals United States
- Lakehouse rentals Memphis
- Guesthouse rentals Memphis
- House rentals Memphis
- Tiny house rentals Mississippi
- House rentals Mississippi
- Townhouse rentals Mississippi
- Beach house rentals Mississippi
- Guesthouse rentals Mississippi
- Lakehouse rentals Mississippi
- House rentals Downtown Memphis
- House rentals Oxford
- Townhouse rentals Oxford
- Pet-friendly rentals DeSoto County
- Rentals with a fireplace DeSoto County
- Rentals with a washer and dryer DeSoto County
- Rentals with pools DeSoto County
- Rentals with a fire pit DeSoto County
- Kid-friendly rentals DeSoto County
- Rentals with a patio DeSoto County
- Fitness-friendly rentals DeSoto County
- Monthly Rentals DeSoto County
- Rentals with outdoor seating DeSoto County
- Rentals with lake access DeSoto County
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes