Pet-friendly vacation rentals in DeSoto County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in DeSoto County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Southaven

4.9 out of 5 average rating, 42 reviews

Large Groups & Special Occasions!

Enjoy our spacious home and friendly community. Sleeping for over 20 guests, a gym, office, recreation areas, and expansive driveway, perfect for short or long stays and groups of all sizes. Plans for over 40 visitors or large outdoor activities require an additional accommodation fee. We request the garage remain closed during mandated 10 PM outdoor quiet hours. No guns or smoke inside. No vehicles on grass. Near: *Tanger Outlets~5min *Landers Center~6min *MEM Airport~17min *Beale Street~22min

Guest favorite

Home in Hernando

4.89 out of 5 average rating, 226 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Guest favorite

Home in Southaven

5 out of 5 average rating, 28 reviews

New Home around Snowden Grove Park & Silo Square

It’s fresh, it’s clean and it’s brand new!! Located in Southaven’s Metro area and nested in a peaceful neighborhood, this spacious 4-bedroom brand new home offers comfort, relaxation, and easy access to places of attractions; only 5 minutes from Snowden Grove Baseball Field, Bankplus Amphitheater and Snowden Grove Park, 5 minutes from Silo Square, where you will find all local restaurants, 8 minutes from Landers Center, 15 minutes from downtown Memphis, 10 minutes from Memphis Int’l Airport…

Guest favorite

Home in Southaven

4.81 out of 5 average rating, 162 reviews

Near Memphis, TN Mi Casa Es Su Casa

CLOSE TO MEMPHIS, TN 10 MINUTES AWAY VERY big house!! Walk-in closets. A 26X21 area with a pool table, playing card table, plenty of room for kids to play, entertain OR hang out. Front porch to enjoy the nights AND back porch to have your cookout. Driveway for several vehicles. Two homes on the property, rented separately. Like in the country BUT in the city. Tranquil, Safe, Close to shopping areas, gas stations, close to highways. Close to Snowden Grove. Very close to Memphis, TN

Guest favorite

Home in Southaven

5 out of 5 average rating, 11 reviews

The Cozy Miss - Pet friendly!

Welcome to Cozy Miss! Nestled in a safe, cozy neighborhood, this modern oasis offers everything for a comfy, stylish stay. It's perfect for unwinding after a day in Memphis. The fenced backyard features a grill and plenty of space for pets. We only ask that you don't leave your pet unattended at the home! A fully stocked kitchen, dedicated workspace, Smart Roku TV, and games are included. - 14 mins to Graceland - 15 mins to MEM airport Please note: Guests must be 25 or older to book.

Guest favorite

Guesthouse in Olive Branch

5 out of 5 average rating, 15 reviews

Private Pool House at Bethel Gardens -Olive Branch

Stay, relax and enjoy the newly remodeled private Pool House. The Pool House is located on 12 peaceful acres in Olive Branch, MS. You have your own kitchen, bathroom and 1 loft bedroom. Bring your swimming suit! Soak up the Mississippi sun and unwind by the pool! Enjoy your morning coffee or your evening glass of wine on the patio and just maybe you will see some deer on the property. Minimum of 30 day booking. PLEASE READ HOUSE RULES! Partial or full refund on cleaning fees

Guest favorite

Guesthouse in Hernando

5 out of 5 average rating, 106 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

Home in Southaven

5 out of 5 average rating, 16 reviews

~Southern~Comfort 4bd/2ba~Retreat~

About This Place Relax in this warm and inviting newly built home centrally located in Southaven, MS, close to shops, restaurants, and major businesses and 20 minutes from all downtown Memphis attractions! It is set up to accommodate students, travel nurses, remote workers, business travelers, and families for short, 30+day stays. It has 4 bedrooms and 2 full bathrooms, spacious backyard and fully furnished covered patio. Ask about late checkout and essential worker discounts!

Guest favorite

Home in Hernando

5 out of 5 average rating, 24 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Guest favorite

Home in Southaven

5 out of 5 average rating, 12 reviews

Stylish Cottage in Silo Square near Snowden Grove

This stylish new construction home is a home away from home. It is centrally located in the heart of the Snowden Grove community in Silo Square. This location not only boosts close proximity to Snowden Grove Park (Concert Amphitheater, Baseball, Soccer, Tennis), it is steps away from local shops and restaurants. 10 miles to Memphis Airport, 12 miles to Graceland Mansion. The home offers optional concierge service (i.e. stocked fridge/pantry) at an additional cost.

Guest favorite

Farm stay in Southaven

4.99 out of 5 average rating, 91 reviews

“The Longhorn House” at Blue Haze Farms

Get away from it all when you stay under the stars at our rustic tiny house. Kayak the lake or just take a hike. Sink into the memory foam mattress with luxurious linens and watch a movie on one of the smart TVs. Listen to some of our vintage records or play some old fashion board games ! Just want to relax? Curl up in the swing chair and watch our miniature Longhorns graze. Conveniently located south of Memphis, TN & Graceland. Relax. Unwind. Rejuvenate.

Guest favorite

Home in Olive Branch

4.9 out of 5 average rating, 29 reviews

Two story home in a cozy cove

In the heart of Olive Branch, just minutes from local restaurants and shopping, you’ll find this warm and welcoming newly renovated home. With the main suite downstairs, two bedrooms, and one bathroom upstairs, you’ll have plenty of room for all of your guests. Being just 15 minutes from Southaven and 30 minutes from downtown Memphis, you’re sure to have a fun filled stay.