Pet-friendly vacation rentals in DeSoto County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in DeSoto County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Southaven

4.9 out of 5 average rating, 39 reviews

Large Groups & Special Occasions!

Enjoy our spacious home and friendly community. Sleeping for over 20 guests, a gym, office, recreation areas, and expansive driveway, perfect for short or long stays and groups of all sizes. Plans for over 40 visitors or large outdoor activities require an additional accommodation fee. We request the garage remain closed during mandated 10 PM outdoor quiet hours. No guns or smoke inside. No vehicles on grass. Near: *Tanger Outlets~5min *Landers Center~6min *MEM Airport~17min *Beale Street~22min

Guest favorite

Home in Hernando

4.89 out of 5 average rating, 226 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Superhost

Home in Southaven

4.89 out of 5 average rating, 64 reviews

Newly constructed, peaceful and cozy home

Newly constructed home built in 2019. The neighborhood is very quiet and safe. The home is 10 minutes from Memphis Airport; 2 minutes from I-55; less than 15 minutes from downtown Memphis, Orpheum Theater, FedEx Forum, Beale Street, Bass Pro Shop, and many other attractions; 2 minutes from North Creek Golf Course; 5 minutes away from restaurants, malls, grocery stores, Walmart, Target, movies theaters, etc. The perfect place to relax after a long eventful day! 6 exterior security cameras.

Guest favorite

Home in Southaven

4.81 out of 5 average rating, 162 reviews

Near Memphis, TN Mi Casa Es Su Casa

CLOSE TO MEMPHIS, TN 10 MINUTES AWAY VERY big house!! Walk-in closets. A 26X21 area with a pool table, playing card table, plenty of room for kids to play, entertain OR hang out. Front porch to enjoy the nights AND back porch to have your cookout. Driveway for several vehicles. Two homes on the property, rented separately. Like in the country BUT in the city. Tranquil, Safe, Close to shopping areas, gas stations, close to highways. Close to Snowden Grove. Very close to Memphis, TN

Guest favorite

Home in Southaven

5 out of 5 average rating, 11 reviews

The Cozy Miss - Pet friendly!

Welcome to Cozy Miss! Nestled in a safe, cozy neighborhood, this modern oasis offers everything for a comfy, stylish stay. It's perfect for unwinding after a day in Memphis. The fenced backyard features a grill and plenty of space for pets. We only ask that you don't leave your pet unattended at the home! A fully stocked kitchen, dedicated workspace, Smart Roku TV, and games are included. - 14 mins to Graceland - 15 mins to MEM airport Please note: Guests must be 25 or older to book.

Guest favorite

Guesthouse in Hernando

5 out of 5 average rating, 103 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

Home in Southaven

5 out of 5 average rating, 15 reviews

~Southern~Comfort 4bd/2ba~Retreat~

About This Place Relax in this warm and inviting newly built home centrally located in Southaven, MS, close to shops, restaurants, and major businesses and 20 minutes from all downtown Memphis attractions! It is set up to accommodate students, travel nurses, remote workers, business travelers, and families for short, 30+day stays. It has 4 bedrooms and 2 full bathrooms, spacious backyard and fully furnished covered patio. Ask about late checkout and essential worker discounts!

Guest favorite

Home in Hernando

5 out of 5 average rating, 24 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Guest favorite

Farm stay in Southaven

4.99 out of 5 average rating, 89 reviews

“The Longhorn House” at Blue Haze Farms

Get away from it all when you stay under the stars at our rustic tiny house. Kayak the lake or just take a hike. Sink into the memory foam mattress with luxurious linens and watch a movie on one of the smart TVs. Listen to some of our vintage records or play some old fashion board games ! Just want to relax? Curl up in the swing chair and watch our miniature Longhorns graze. Conveniently located south of Memphis, TN & Graceland. Relax. Unwind. Rejuvenate.

Guest favorite

Home in Southaven

4.9 out of 5 average rating, 20 reviews

Cozy 4BR 2BA Southaven Home

This cozy 4-bedroom home in the heart of Southaven, MS, blends comfort with Southern charm, perfect for families or a friends' getaway. With a warm, inviting atmosphere that balances simplicity and functionality, it's conveniently located near attractions, dining, and shopping. Whether you're looking for a relaxing retreat or an adventure-filled stay, this charming home offers the ideal setting for your visit.

Guest favorite

Home in Southaven

5 out of 5 average rating, 26 reviews

Brand New Home —in the heart of Southaven

Be our guests and you will be blessed! Located in Southaven Metro area and nested in a peaceful neighborhood, this spacious 4-bedroom brand new home offers comfort, relaxation, and easy access to restaurants, public parks, sport venues, shopping centers, convention centers, grocery stores, casino resorts and more. All guests who have stayed here rated this HOME, 5 stars. ⭐️⭐️⭐️⭐️⭐️

Guest favorite

Home in Hernando

4.95 out of 5 average rating, 37 reviews

Cozy 2-Bedroom Home in downtown Hernando

Enjoy this cozy 2-bedroom 2-bathroom house in walking distance to restaurants, bars, and boutiques for shopping. This cozy home is located in the town of Hernando, Mississippi. With less than a 30 minute drive to Memphis , a 10 minute drive to Southaven, and less than an hour to Oxford, this location offers various day trip opportunities!