Guesthouse vacation rentals in Durham County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Durham County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Durham County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Raleigh
4.87 out of 5 average rating, 435 reviewsAdorable 1BR studio in Five Points
Guesthouse in Carrboro
4.85 out of 5 average rating, 411 reviewsGuest cottage close to downtown Carrboro
Guesthouse in Hillsborough
4.96 out of 5 average rating, 333 reviewsHummingbird Retreat
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 340 reviewsCozy Secluded Accessible West Wing
Guesthouse in Apex
4.92 out of 5 average rating, 347 reviewsCountry place close to all Triangle locations
Guesthouse in Cary
4.92 out of 5 average rating, 295 reviewsCentral to Everything, Renovated, Dog Friendly.
Guesthouse in Raleigh
4.98 out of 5 average rating, 889 reviewsWalk to downtown. Private stylish studio cottage.
Guesthouse in Durham
4.87 out of 5 average rating, 181 reviewsRockwood Oasis Studio BR Bath no kitchen
Guest house rentals with a patio
Guesthouse in Raleigh
4.9 out of 5 average rating, 120 reviewsRetreat La Cabana
Guesthouse in Raleigh
4.99 out of 5 average rating, 131 reviewsDowntown Private Oasis w/ Cal King
Guesthouse in Chapel Hill
4.9 out of 5 average rating, 51 reviewsThe cozy home
Guesthouse in Raleigh
5.0 out of 5 average rating, 27 reviewsCarriage House Studio in Quiet Neighborhood
Guesthouse in Holly Springs
5.0 out of 5 average rating, 83 reviews"Wit's End" welcomes you! 2BR comfy guest house
Guesthouse in Chapel Hill
4.81 out of 5 average rating, 31 reviewsGuesthouse + Access to Morgan Creek Trail
Guesthouse in Raleigh
4.99 out of 5 average rating, 82 reviewsNeighborhood Loft
Guesthouse in Raleigh
5.0 out of 5 average rating, 41 reviewsThe Nest: Private Downtown Guest House
Guest house rentals with a washer and dryer
Guesthouse in Durham
4.93 out of 5 average rating, 89 reviewsAdorable + private guesthouse close to downtown
Guesthouse in Durham
4.83 out of 5 average rating, 36 reviewsProfessor's Cottage in Duke Park.
Guesthouse in Durham
4.93 out of 5 average rating, 41 reviewsDuplex filled with natural light
Guesthouse in Durham
5.0 out of 5 average rating, 3 reviews* Private Garage * Studio Apartment * Pet Friendly
Guesthouse in Durham
5.0 out of 5 average rating, 15 reviews1 Bedroom Apartment Overlooking Duke Campus East
Guesthouse in Durham
4.97 out of 5 average rating, 35 reviewsDownUnder @DukePark Standing Desk Charming & Clean
Guesthouse in Durham
4.95 out of 5 average rating, 43 reviewsBeautiful Alley House 2 Blocks to Duke + Downtown.
Guesthouse in Durham
4.94 out of 5 average rating, 87 reviewsSunny New Carriage House off Duke’s East Campus
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