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Family-friendly vacation rentals in Mesa County

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mesa County

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Farm stay in Glade Park

4.87 out of 5 average rating, 560 reviews

Cozy Rustic Colorado Cabin!

Cozy Rustic Cabin, located on a working horse ranch on top of the Colorado National Monument, 30 min from Grand Junction, CO. This location is perfect for those seeking a unique place to stay while enjoying all the adventures available around the area including hiking trails, horseback riding, ATV riding, hunting, and some of the best mountain biking around. There is beautiful aspen covered,alpine high country nearby as well as red rock desert/ formations including a series of natural arches.

Home in Paonia

4.92 out of 5 average rating, 675 reviews

Kale's Private & Romantic Cottage - King, Kitchen

Kale's Cottage features a kind size bed and is the epitome of unique and comfortable stays in Western Colorado. Our award-winning, pet-friendly Solargon boasts an elegant design, and is located just a half-mile walk away from the charming downtown of Paonia. The 374 sq ft space offers a fully stocked kitchen, seasonal wood stove, work/dining table & spacious private bathroom with shower. Whether for a special getaway, work, hiking, business or adventure, this is your perfect home away from home.

Home in Grand Junction

4.89 out of 5 average rating, 247 reviews

Hill View in the Ridges

What you will find during your stay here? Awe-inspiring natural beauty of the Red Rocks of the Colorado National Monument. Exhilarating outdoor adventures including hiking, skiing. Hundreds of miles of world-class mountain biking trails such as Kokopelli Trail. Incredible whitewater rafting on the Colorado River. Stunning golf courses whose green fairways are juxtaposed against the craggy Redland desert. All with in miles of the Redlands Golf course, Lunch Loop bike trail and Two Rivers Winery.

Guest suite in Crawford

4.97 out of 5 average rating, 588 reviews

Crawford’s Mountain View Getaway

Enjoy a stunning Rocky Mountain View of Needle Rock and the Pitkin Range. The space has many amenities for 1 to 12 people. Families, hunters, couples, all are welcome to enjoy the indoor/outdoor private areas with their rustic southwest decor in the lower level walkout. 1.5 miles from the "last genuine cowtown" Crawford, CO, (you might see a cattle drive going through town), 1 mile from the Crawford Lake, 11 miles to Black Canyon of the Gunnison National Park. Cleaning info in things to note.

Cottage in Grand Junction

4.97 out of 5 average rating, 118 reviews

Sycamore Cottage a cozy carriage house

This delightful 523 sq.ft. 1937 cottage is located in the heart of Grand Junction close to downtown, St.Mary's hospital, popular restaurants and ample shopping opportunities. We are only minutes away from Colorado National Monument. It is convenient to Amtrak, Two Rivers Convention Center and Grand Junction Regional Airport. On a historic street is the carriage house that I have called Sycamore Cottage. A huge old noble Sycamore tree is a focal point in your backyard among other lovely views.

Home in Grand Junction

4.92 out of 5 average rating, 173 reviews

5200SqFt, Hillside Rock In House, Stunning Views

One of a kind 4BR 3BA 5,200 sqft home. Stunning views of the CO Ntl Mnt and entire Grand Valley. Our grandpa, a home builder, designed this rustic house as a masterpiece for his family. He wanted it to be part of nature, so he fit it between trees and inside left exposed the massive sandstone slab on which it’s built. This large house has entertained our family and friends for generations, and we’re thrilled that now you can share it with yours, too. Be in nature but minutes from downtown!

Home in Grand Junction

4.99 out of 5 average rating, 166 reviews

Blue Door Farm Vacation Rental

Beautiful, sunny, and brand-new vacation rental in the heart of southwestern Colorado's peach and wine country. Blue Door Farm Vacation Rental LLC offers full accommodations for 1 to 6 guests, with sweeping views of the Grand Valley from the high desert to the Grand Mesa. It is a 15 minute drive to downtown Palisade and Grand Junction, and only 5 minutes to one hour's drive to amazing year-round outdoor recreation, including hiking, biking, skiing, agritourism, music festivals and wineries.

Rental unit in Grand Junction

4.92 out of 5 average rating, 782 reviews

HOME AWAY HAVEN - Private Entrance

We welcome all, to settle into over 600 s.f. of above average basement living. LOCATED ON HIGHWAY 50 (we run parallel w/I-70), within a secured, gated 3/4 fenced property, 10 minutes from downtown Grand Junction. Two nice queen beds sleeping 4, couch w/recliners, futon, large electric reclining chair, twin & full inflatable mattresses, two sleep pads, full kitchen, 3/4 bath w/hot shower, nice towels, ample parking. Smart t.v. or Roku in bedrooms. WIFI Kids Under 3 Free All Smoking outside.

Guest suite in Fruita

4.97 out of 5 average rating, 216 reviews

Bookcliff Ranch Casita

The Bookcliff Ranch Casita is on a secluded, "end of the road" 110 acre ranch a short 5 mile drive from the quaint, friendly, always active town of Fruita - a mountain biker's paradise with 100s of miles of biking & hiking trails. The Casita is close to the North Fruita Desert Trail Head's biking, hiking, horse, & OHV trails. The casita includes access to our pool. We are pet friendly with a small $30 one time fee per dog. Trailer parking and options for horse boarding are also available.

Guest suite in Paonia

4.99 out of 5 average rating, 298 reviews

Very spacious private floor with beautiful views.

Self check-in to the space makes it especially convenient for travelers no matter when you arrive. Views of the surrounding mountains are breathtaking.Our place is good for couples, solo adventurers, and business travelers. The space is on your own floor, completely separated from our upstairs space and with a private entrance. Enjoy a self-serve continental breakfast with freshly ground coffee and an assortment of teas. The location is quiet and private, yet so close to town.

Barn in Palisade

4.9 out of 5 average rating, 564 reviews

Beautiful Vineyard Barn House

Our spacious and newly renovated large barn has a beautiful view of the Grand Valley. Relax among the vines under Mt. Garfield. Drink wine at one of the many wineries. Enjoy peace and quiet while picking a peach in the orchard or grapes in the vineyard. We are conveniently located 2 miles from downtown Palisade and 13 miles from downtown Grand Junction. From skiing, to mountain biking, to rafting, to hiking, and road biking there are outdoor activities nearby for all levels.

Rental unit in Grand Junction

4.93 out of 5 average rating, 268 reviews

In town, bike friendly, modern apt.

Enjoy Grand Junction in our newly renovated modern apartment. Centrally located with only a short walk to Main Street's many great restaurants! Our favorites are Bin 707, Il Bistro Italiano, Cafe Sol, Dream Cafe, and Pablo's Pizza. GJ's Lunch Loop trails are only a 10 minute ride away. Check out this site for top spots to visit! https://www.tripadvisor.com/Attractions-g33450-Activities-Grand_Junction_Colorado.html

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Popular amenities for Mesa County family-friendly rentals

Free parking on premises

Air conditioning

Family-friendly home rentals with a hot tub

Home in Montrose

4.91 out of 5 average rating, 103 reviews

Stunning Views, Hot Tub, 7 BDRM 4 BTH

Rental unit in Grand Junction

4.85 out of 5 average rating, 439 reviews

Grand Valley Cozy Retreat

Guest suite in Crawford

4.97 out of 5 average rating, 588 reviews

Crawford’s Mountain View Getaway

Home in Grand Junction

4.96 out of 5 average rating, 150 reviews

Little Park Road Retreat - Hot Tub with a View

Guest suite in Fruita

5 out of 5 average rating, 96 reviews

Western Colorado Bikers' Oasis

Home in Grand Junction

4.97 out of 5 average rating, 807 reviews

Grand Junction Bike Hotel & Hot Tub

Family- and pet-friendly home rentals

Cabin in Cedaredge

4.78 out of 5 average rating, 36 reviews

Cabin #4 at Thunder Mountain Lodge

Home in Cedaredge

5 out of 5 average rating, 61 reviews

Gorgeous CedarGate House Cedaredge CO- Mountains!

Rental unit in Grand Junction

4.64 out of 5 average rating, 202 reviews

Cozy Studio

Home in Hotchkiss

4.95 out of 5 average rating, 164 reviews

The Moon House. Come mingle with the stars.

Yurt in Gateway

4.87 out of 5 average rating, 269 reviews

Unaweep Yurt and Thimble Rock (WiFi)

Home in Fruita

4.9 out of 5 average rating, 39 reviews

Juniper: Jetted Tub, Dog Friendly & Fire Pit!

Home in Palisade

4.8 out of 5 average rating, 112 reviews

The Magnolia House, Victorian Wine Retreat

Guest suite in Grand Junction

4.92 out of 5 average rating, 255 reviews

Deer View Cottage

Family-friendly home rentals with a pool

Guest suite in Fruita

4.97 out of 5 average rating, 216 reviews

Bookcliff Ranch Casita

Rental unit in Grand Junction

4.91 out of 5 average rating, 79 reviews

St. Mary's Hospital Haven

Guest suite in Fruita

5 out of 5 average rating, 96 reviews

Western Colorado Bikers' Oasis

Condo in Grand Junction

4.92 out of 5 average rating, 12 reviews

Ideal Relaxing Location for Outdoor Adventurers

Destinations to explore