House vacation rentals in Saint Charles
Find and book unique houses on Airbnb
Top-rated house rentals in Saint Charles
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Saint Charles house rentals
House rentals with a pool
Home in Ballwin
4.95 out of 5 average rating, 124 reviewsPrivate indoor pool & sauna
Home in Saint Charles
4.92 out of 5 average rating, 150 reviewsClark Brick House w/ Pool | Historic St. Charles
Home in Creve Coeur
4.96 out of 5 average rating, 48 reviewsBlair's Pool House - Creve Couer Hot Tub Game Room
Home in Saint Charles
4.91 out of 5 average rating, 33 reviewsStunning 4 bedroom, 4 bath, pool, theater, etc
Home in Dittmer
4.95 out of 5 average rating, 420 reviewsHoneymoon Suite Camp Skullbone In The Woods
Home in Wentzville
5 out of 5 average rating, 38 reviewsSpacious (basement) apartment in Wentzville
Home in The Hill
4.97 out of 5 average rating, 71 reviewsVitale’s on the Hill
Home in Gray Summit
4.88 out of 5 average rating, 136 reviewsSunset Mountain Privacy
Weekly house rentals
Home in The Hill
4.85 out of 5 average rating, 164 reviewsCozy Family Cottage | Perfect Location on the Hill
Home in Richmond Heights
4.99 out of 5 average rating, 156 reviewsZOO, Wash U, close to Clayton,Parking & Safe!
Home in Millstadt
4.95 out of 5 average rating, 277 reviewsDeluxe Barndominium | King bed + Pkg
Home in Tower Grove South
4.88 out of 5 average rating, 109 reviews☆ Hot Tub ☆ New Renovated ☆ Massage Shower ☆Yard☆
Home in O'Fallon
4.85 out of 5 average rating, 171 reviewsThe Gathering Home 3bdrm 1 bth
Home in The Hill
4.87 out of 5 average rating, 243 reviewsCozy House on The Hill
Home in St. Louis
4.83 out of 5 average rating, 183 reviewsBeautiful and Spacious 3BR Newly Renovated Home
Home in Central West End
4.98 out of 5 average rating, 102 reviewsLuxe Manor Style 3 Floors Home | 6BR / ABODEbucks
Private house rentals
Home in Florissant
4.77 out of 5 average rating, 62 reviewsMore bang! Less buck! Nice Quiet Neighborhood!
Home in Belleville
4.9 out of 5 average rating, 102 reviewsSpacious 2/1 w/large yard only 20 min to STL Arch
Home in Defiance
4.95 out of 5 average rating, 43 reviewsThe Niederschulte House
Home in Saint Charles
4.96 out of 5 average rating, 72 reviewsOld Charm on Fifth 4B 2.5B/ 10 Guests 5min to Main
Home in St. Louis
4.98 out of 5 average rating, 94 reviews4.98 star Historic StL City Pet lovers Gem Arch +
Home in St. Louis
4.81 out of 5 average rating, 184 reviewsHistoric Brick Home by Forest Park/Wash U.
Home in Pacific
4.92 out of 5 average rating, 106 reviewsPacific Palace, super unique!
Home in St. Louis
4.92 out of 5 average rating, 358 reviewsSunny South City Guest House
Quick stats about house rentals in Saint Charles
Total rentals
100 properties
Total number of reviews
7.7K reviews
Family-friendly rentals
90 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with dedicated workspaces
70 properties have a dedicated workspace
Wifi availability
100 properties include access to wifi
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