Guesthouse vacation rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Encinitas
4.86 out of 5 average rating, 228 reviewsSunset/Ocean View Guest House! Minutes to Beach
Nov 18 – 25
Guesthouse in San Diego
4.92 out of 5 average rating, 366 reviewsCozy 1-bdr apt in Normal Heights near Adams Ave
Jan 8 – 15
Guesthouse in Chula Vista
4.95 out of 5 average rating, 475 reviewsPrivate Casita in Great Eastlake Neighborhood
Oct 17 – 24
Guesthouse in San Diego
4.91 out of 5 average rating, 380 reviewsNorth Park Cottage
Apr 15 – 22
Guesthouse in San Diego
4.96 out of 5 average rating, 211 reviewsNorth Park, San Diego's Best At Your Doorstep
Jun 3 – 10
Guesthouse in San Diego
4.97 out of 5 average rating, 292 reviewsPrivate Guest House with a View
Aug 6 – 13
Guesthouse in San Diego
4.84 out of 5 average rating, 315 reviewsPacific Beach Guest House With Garage and A/C
Dec 14 – 21
Guesthouse in San Diego
4.96 out of 5 average rating, 251 reviewsYour Kensington Bungalow
Sep 27 – Oct 4
Guest house rentals with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 106 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Oct 22 – 29
Guesthouse in San Diego
4.98 out of 5 average rating, 123 reviewsPrivate Studio Cottage with Outdoor Patio
Jan 1 – 8
Guesthouse in San Diego
4.93 out of 5 average rating, 147 reviewsCentral studio w/ private outdoor space & parking
Mar 23 – 30
Guesthouse in Oceanside
4.94 out of 5 average rating, 154 reviewsDetached, Private Cottage! Fenced, PET friendly!
Mar 12 – 19
Guesthouse in La Mesa
4.98 out of 5 average rating, 250 reviewsLa Mesa Suite
Apr 7 – 14
Guesthouse in San Diego
4.99 out of 5 average rating, 151 reviewsAdorable cottage in Talmadge
Aug 4 – 11
Guesthouse in San Diego
4.99 out of 5 average rating, 107 reviewsModern Guest House with Patio, Parking, & Laundry
Jun 5 – 12
Guesthouse in La Mesa
4.99 out of 5 average rating, 167 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.96 out of 5 average rating, 208 reviewsPrivate beach guesthouse w/ private parking
Oct 3 – 10
Guesthouse in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
Sep 3 – 10
Guesthouse in San Diego
4.91 out of 5 average rating, 190 reviewsSTUNNING Casita with a View!!
Oct 13 – 20
Guesthouse in La Mesa
4.99 out of 5 average rating, 133 reviewsStunning Guest House 15 min. from Zoo, Downtown
Oct 16 – 23
Guesthouse in El Cajon
4.98 out of 5 average rating, 190 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Apr 6 – 13
Guesthouse in San Diego
4.99 out of 5 average rating, 131 reviewsCarrie’s North Park Casita, in Heart of San Diego
Oct 6 – 13
Guesthouse in San Diego
4.98 out of 5 average rating, 117 reviewsCasita Hermosa - Close to everything in San Diego
Nov 23 – 30
Guesthouse in San Diego
4.97 out of 5 average rating, 327 reviewsPrivate Guesthouse with Bay View Deck
May 24 – 31
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
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