Guesthouse vacation rentals in San Diego County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in San Diego
4.93 out of 5 average rating, 449 reviewsPrivate Cottage in Walkable North Park w/AC
Guesthouse in San Diego
4.91 out of 5 average rating, 357 reviewsLa Casita - Fully Updated Casita in Mission Hills
Guesthouse in Vista
4.87 out of 5 average rating, 243 reviewsPRIVATE CASITA nestled in a great neighborhood
Guesthouse in Encinitas
4.96 out of 5 average rating, 347 reviewsCardiff by the Sea Beach Bungalow
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Guesthouse in San Diego
4.97 out of 5 average rating, 509 reviewsCentral & Serene Secret Garden Guesthouse
Guesthouse in San Diego
4.94 out of 5 average rating, 335 reviewsThe BEST NEST Clean, peaceful, private, affordable
Guesthouse in Encinitas
4.86 out of 5 average rating, 228 reviewsSunset/Ocean View Guest House! Minutes to Beach
Guest house rentals with a patio
Guesthouse in San Diego
4.99 out of 5 average rating, 152 reviewsAdorable cottage in Talmadge
Guesthouse in San Diego
4.98 out of 5 average rating, 101 reviewsKing Bed, Free Parking, Fast Wi-Fi, Full Kitchen
Guesthouse in San Diego
5.0 out of 5 average rating, 109 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Guesthouse in San Diego
4.92 out of 5 average rating, 153 reviewsCentral studio w/ private outdoor space & parking
Guesthouse in Lakeside
4.94 out of 5 average rating, 103 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in La Mesa
4.97 out of 5 average rating, 133 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Guesthouse in Oceanside
4.94 out of 5 average rating, 158 reviewsDetached, Private Cottage! Fenced, PET friendly!
Guesthouse in La Mesa
4.97 out of 5 average rating, 119 reviewsSan Diego Newly Built Private Guesthouse (Sleep 5)
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.98 out of 5 average rating, 185 reviewsNorth Park Garden Retreat Casita
Guesthouse in San Diego
4.94 out of 5 average rating, 105 reviewsAdorable studio/self check-in & off street parking
Guesthouse in San Diego
4.95 out of 5 average rating, 111 reviewsRelax in a Centrally Located, Modern Guest House
Guesthouse in San Diego
4.96 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
Guesthouse in San Diego
4.93 out of 5 average rating, 148 reviewsPoint Loma Private Apartment
Guesthouse in San Diego
4.95 out of 5 average rating, 212 reviewsPrivate beach guesthouse w/ private parking
Guesthouse in San Diego
4.91 out of 5 average rating, 153 reviewsRelaxing Oasis - short walk to shops & recreation
Guesthouse in San Diego
4.87 out of 5 average rating, 420 reviewsThe Golden Hill mosaic "casita"
Destinations to explore
- House rentals United States
- Guesthouse rentals United States
- House rentals San Diego
- Guesthouse rentals San Diego
- Guesthouse rentals California
- House rentals California
- House rentals Joshua Tree
- Guesthouse rentals Palm Springs
- House rentals Palm Springs
- Townhouse rentals San Diego County
- Cabin rentals San Diego County
- Beachfront rentals San Diego County
- House rentals San Diego County
- Rentals with a kayak San Diego County
- Fitness-friendly rentals San Diego County
- Tiny house rentals San Diego County
- Luxury rentals San Diego County
- Villa rentals San Diego County
- Rentals with pools San Diego County
- Rentals with a sauna San Diego County
- Campsite rentals San Diego County
- Condo rentals San Diego County
- Family-friendly rentals San Diego County
- Rentals with lake access San Diego County
- Serviced apartment rentals San Diego County
- Monthly Rentals San Diego County
- Rentals with an accessible height toilet San Diego County
- Rentals with a washer and dryer San Diego County
- Rentals with a balcony San Diego County
- Bungalow rentals San Diego County
- Bed and breakfasts San Diego County
- Loft rentals San Diego County
- Tent rentals San Diego County
- Waterfront rentals San Diego County
- Rentals with a beach view San Diego County
- Hotel rentals San Diego County
- Rentals with an EV charger San Diego County
- Smoking-friendly rentals San Diego County
- RV rentals San Diego County
- Rentals with outdoor seating San Diego County
- Rentals with an accessible height bed San Diego County
- Rentals with a hot tub San Diego County
- Rentals with a fireplace San Diego County
- Apartment rentals San Diego County
- Rentals with beach access San Diego County
- Kid-friendly rentals San Diego County
- Resort rentals San Diego County
- Private suite rentals San Diego County
- Rentals with a fire pit San Diego County
- Rentals with a home theater San Diego County
- Pet-friendly rentals San Diego County
- Cottage rentals San Diego County
- Rentals with a patio San Diego County
- Rentals with breakfast San Diego County
- Wheelchair accessible rentals San Diego County
- Vacation home rentals San Diego County
- Farmstay rentals San Diego County
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes