Hotel vacation rentals in South Carolina
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Top-rated hotel rentals in South Carolina
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Vacation rentals for every style
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Popular amenities for South Carolina hotel rentals
Family-friendly hotel rentals
Hotel room in Edisto Island
5.0 out of 5 average rating, 12 reviewsWyndham Ocean Ridge - Edisto Island ** 1 Bedroom
Jun 14 – 21
Resort in Hilton Head Island
5.0 out of 5 average rating, 4 reviewsOceanfront, Brand new Luxury Suite!!
Apr 19 – 26
Resort in Myrtle Beach
2 Bdrm - South Beach Resort - Myrtle Beach, SC
Jan 2 – 7
Resort in Myrtle Beach
Myrtle Beach, Ocean Front Apt, July 7- July 14
Jan 1 – 8
Hotel in Charleston
4.77 out of 5 average rating, 43 reviewsCharming Historic Inn*
Nov 29 – Dec 6
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Jun 14 – 21
Resort in Myrtle Beach
5.0 out of 5 average rating, 4 reviews1 bdrm condo, South Beach Resort, Beach Access
Nov 10 – 17
Hostel in Charleston
4.72 out of 5 average rating, 384 reviewsThe Goldman Room @ The Annex
Apr 23 – 30
Hotel rentals with a pool
Pension in Myrtle Beach
4.65 out of 5 average rating, 20 reviewsLaurel Court 210 in Kingston resort, Pools & Beach
Feb 18 – 25
Resort in Pawleys Island
4.62 out of 5 average rating, 13 reviewsBubbles Up at Litchfield By The Sea
Jan 24 – 31
Aparthotel in Murrells Inlet
4.94 out of 5 average rating, 71 reviewsInlet Cottage Guests Suite, Too in Murrells Inlet
Mar 20 – 27
Resort in Myrtle Beach
5.0 out of 5 average rating, 27 reviewsAmazing Ocean views! Pool, lazy river, hot tub
May 23 – 30
Hotel in North Charleston
4.78 out of 5 average rating, 118 reviewsThe Starlight Motor Inn - King + Pool!
Jun 3 – 10
Resort in North Myrtle Beach
4.87 out of 5 average rating, 52 reviewsTilghman Beach and Golf Resort 3 bed, 3 full bath
Jan 29 – Feb 5
Room in Irmo
5.0 out of 5 average rating, 10 reviewsRelax in beach themed room.
Jun 6 – 13
Resort in Myrtle Beach
4.63 out of 5 average rating, 40 reviewsOceanfront Resort with a View - Freshly Renovated
Oct 31 – Nov 7
Hotel rentals with a patio
Casa particular in Hilton Head Island
New place to stayHeritage Classic 2025 Villa
Feb 5 – 12
Room in Spartanburg
4.96 out of 5 average rating, 24 reviewsLovely 1 br/1 private bath.
Mar 21 – 28
Nature lodge in Greenville County
4.88 out of 5 average rating, 8 reviewsCabin near Pretty Place!
Sep 26 – Oct 3
Resort in Myrtle Beach
4.9 out of 5 average rating, 30 reviews2bd 2ba ocean view condo
Oct 5 – 12
Hotel in Hilton Head Island
5.0 out of 5 average rating, 9 reviewsCharming Hilton Head Harbor Point Resort 2bd Suite
Jul 25 – Aug 1
Boutique hotel in Sunset
4.56 out of 5 average rating, 9 reviews"Muskrat" room at Wilderness Retreat Center
May 21 – 28
Resort in Myrtle Beach
5.0 out of 5 average rating, 11 reviewsBeautiful 2 bedroom resort at Myrtle Beach
Apr 1 – 8
Hotel in Hilton Head Island
New place to stay2 BR Villa @ Barony Beach Club
Dec 20 – 27
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