Bed and breakfast vacation rentals in Upstate South Carolina
Find and book unique bed and breakfast rentals on Airbnb
Top-rated bed and breakfast rentals in Upstate South Carolina
Guests agree: these bed and breakfast rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Upstate South Carolina bed and breakfast rentals
Family-friendly bed and breakfast rentals
Bed and breakfast in Maggie Valley
4.94 out of 5 average rating, 298 reviewsHolly Tree Bed & Breakfast - Maggie's Room
Sep 7 – 14
Place to stay in Irmo
4.99 out of 5 average rating, 82 reviewsLake Murray Retreat
Mar 23 – 30
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Dec 20 – 27
Room in Jefferson
4.95 out of 5 average rating, 65 reviewsOne Room - Sleeps 2 Guests Queen Bed on Small Farm
Jan 8 – 15
Room in Grover
5.0 out of 5 average rating, 16 reviewsFormer White House Chefs home (Nature & Earth Rm)
Jan 20 – 27
Hotel room in Tryon
4.83 out of 5 average rating, 47 reviewsGreenLife Inn at Mimosa Room 208
Feb 14 – 21
Boutique hotel in Chimney Rock
4.95 out of 5 average rating, 39 reviewsQueen Bedroom - No Cleaning Fees & Free Breakfast!
Jan 20 – 27
Room in Bryson City
4.65 out of 5 average rating, 72 reviewsThe Waterfall at West Oak Lodging-Queen Guestrm #5
Jan 31 – Feb 7
Bed and breakfast rentals with breakfast
Bed and breakfast in Central
4.99 out of 5 average rating, 143 reviewsEagles Rest Bed & Breakfast (Room 1) Near Clemson!
May 12 – 19
Room in Travelers Rest
4.82 out of 5 average rating, 11 reviewsCastle in the Woods-King Room
May 30 – Jun 6
Bed and breakfast in Chimney Rock
4.94 out of 5 average rating, 18 reviewsBroad River Inn Queen Jacuzzi Rm 6
Jul 30 – Aug 6
Nature lodge in Sylva
4.98 out of 5 average rating, 54 reviewsCabin Suite at the Dillsboro Inn
Jul 20 – 27
Room in Waynesville
4.9 out of 5 average rating, 41 reviews1.Grandview Lodge in the Great Smoky Mountains
Oct 25 – Nov 1
Room in Waynesville
5.0 out of 5 average rating, 43 reviewsGreen Room at Love Lane B & B, walk to Main St.
Oct 23 – 30
Room in Anderson
5.0 out of 5 average rating, 46 reviewsPicket Fence Lodge B&B & Pickle-Ball Court!
Aug 19 – 26
Room in Dillsboro
4.96 out of 5 average rating, 25 reviewsThe Conductor's Quarters @ Whistle Stop Inn.
Apr 10 – 17
Bed and breakfast rentals with a patio
Home in Athens
5.0 out of 5 average rating, 5 reviewsAthensmusic Gem 1 mile from Town
Jul 18 – 25
Room in Greenville
4.96 out of 5 average rating, 99 reviewsB & B/Downtown/Furman/BJU/1
Jul 22 – 29
Room in Hiawassee
4.79 out of 5 average rating, 24 reviewsFrench Room with Private Spa
Oct 27 – Nov 3
Bed and breakfast in Waynesville
Heritage Town View Inn with Farm-Fresh Breakfast
Feb 17 – 24
Bed and breakfast in Belton
4.62 out of 5 average rating, 13 reviewsBelton Bed and Breakfast Historic Suite
Oct 21 – 28
Room in Etowah
5.0 out of 5 average rating, 14 reviewsBed & Breakfast No cleaning fee
Aug 7 – 14
Room in Waynesville
The Palms Suite at Brookside Mountain Mist Inn B&B
Jul 15 – 22
Room in Greenville
4.97 out of 5 average rating, 115 reviewsB & B/Downtown/Furman/BJU/2
Jun 17 – 24
Destinations to explore
- Charlotte Vacation rentals
- Gatlinburg Vacation rentals
- Asheville Vacation rentals
- Pigeon Forge Vacation rentals
- Greenville Vacation rentals
- Columbia Vacation rentals
- Athens Vacation rentals
- Helen Vacation rentals
- Atlanta Vacation rentals
- Nashville Vacation rentals
- Charleston Vacation rentals
- Myrtle Beach Vacation rentals
- Bed and breakfasts United States
- Rentals with breakfast United States
- Rentals with breakfast Charlotte
- Bed and breakfasts Great Smoky Mountains
- Rentals with breakfast Great Smoky Mountains
- Rentals with breakfast Gatlinburg
- Rentals with breakfast South Carolina
- Bed and breakfasts South Carolina
- Rentals with an accessible height toilet Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Monthly Rentals Upstate South Carolina
- Condo rentals Upstate South Carolina
- Rentals with a washer and dryer Upstate South Carolina
- Kid-friendly rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Ski-in/ski-out rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Rentals with a fire pit Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Guesthouse rentals Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- House rentals Upstate South Carolina
- Resort rentals Upstate South Carolina
- Farmstay rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Wheelchair accessible rentals Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Vacation home rentals Upstate South Carolina
- Hotel rentals Upstate South Carolina
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes