Guesthouse vacation rentals in Upstate South Carolina
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Top-rated guesthouse rentals in Upstate South Carolina
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
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Popular amenities for Upstate South Carolina guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Townville
4.88 out of 5 average rating, 231 reviewsLisa’s Lodge
Guesthouse in Salem
4.88 out of 5 average rating, 290 reviewsMountain Edge Loft
Guesthouse in Simpsonville
4.94 out of 5 average rating, 220 reviewsPrivate Suite in Downtown Simpsonville
Guesthouse in Pendleton
4.9 out of 5 average rating, 240 reviewsLa Bella Farm
Guesthouse in Greenville
4.92 out of 5 average rating, 582 reviewsHistoric 19th Century Cabin/Guest House
Guesthouse in Greer
4.95 out of 5 average rating, 239 reviewsExecutive Suite on a farm @GSP Airport
Guesthouse in Saluda
4.98 out of 5 average rating, 254 reviewsCarolina Cottage Guest House
Guesthouse in Rutherfordton
4.96 out of 5 average rating, 225 reviewsTryon Foothills Getaway - NC Wineries - TIEC
Guest house rentals with a patio
Guesthouse in Tryon
4.99 out of 5 average rating, 124 reviews1 bedroom guest house on horse property in Tryon
Guesthouse in Maggie Valley
5.0 out of 5 average rating, 256 reviewsStarswept Studio-Walk to Breakfast and Brewery.
Guesthouse in Watkinsville
4.99 out of 5 average rating, 120 reviewsDowntown guest house with private hot tub & deck
Guesthouse in Clarkesville
5.0 out of 5 average rating, 152 reviewsCozy guest cottage on historic equestrian property
Guesthouse in Sylva
4.96 out of 5 average rating, 135 reviewsWindcrest Loft- charming retreat near the river.
Guesthouse in Hiawassee
4.99 out of 5 average rating, 112 reviewsLakefront Property-SwimmingDock KayaksSUP BoatSlip
Guesthouse in Asheville
4.96 out of 5 average rating, 143 reviewsFirefly Cove Guesthouse
Guesthouse in Winder
4.98 out of 5 average rating, 167 reviewsThe Aspen at The Carriage House
Guest house rentals with a washer and dryer
Guesthouse in Westminster
4.99 out of 5 average rating, 148 reviewsLit'l Bit O' Heaven- Rocky Top Lodge
Guesthouse in Hartwell
4.98 out of 5 average rating, 133 reviewsGuest House at Lake Hartwell
Guesthouse in Greenville
4.97 out of 5 average rating, 179 reviewsThe Biltmore Suite
Guesthouse in Shelby
4.98 out of 5 average rating, 220 reviewsCabin in the Pines
Guesthouse in Toccoa
5.0 out of 5 average rating, 145 reviewsToccoa Guesthouse.
Guesthouse in Hendersonville
5.0 out of 5 average rating, 171 reviewsWhite Squirrel Bungalow
Guesthouse in Watkinsville
4.99 out of 5 average rating, 142 reviewsGallery Carriage House DT Watkinsville w EV
Guesthouse in Pendergrass
4.96 out of 5 average rating, 346 reviewsPeaceful Guesthouse on 15 Acres with Pool
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- Rentals with a washer and dryer Upstate South Carolina
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